Ulrich G. Hofmann
Former Research Associate
Research Interests
HUMAN-MACHINE-INTERFACING
NEURO-ENGINEERING
Goal: Bridging the gap between experimental and simulation approaches for the neuro- and medical sciences.
• Novel high-performance and realtime data acquisition systems for many channels (and neurons).
• Realtime visualization, analysis and data mining in huge neuronal data volumes.
• Modelling of big realistic neuron networks.
CV
2008 Professor, University of Lübeck
2008 Call for a professorate in Biomedical Engineering/Neural Engineering, Reykjavik University, Iceland
2007 Co-Founder of "pro-MedTec GmbH", Lübeck, medical robotics
2005/06 Co-Author "Graduate School Lübeck", DFG-Exzellenzinitiative
2003 Habilitation in Computer Science
1999-2000 Member of the Board of Directors of BioTuL AG, München, Germany
since 1999 Research Associate, University of Lübeck
1997-1998 Postdoctoral Scholar, Feodor-Lynen-Fellow, Division of Biology, California Institute of Technology, Pasadena, CA. "Technology for multisite neuronal recordings"
1996 Research Associate, HCM-Fellow, Institutionen för Fysikalisk Kemi, Åbo Akademi, Turku, Finland. "Ultra-microscopy and surface functionalization of semiconducors"
1993-1996 Research Assistant; Physics Department, Technische Universität München.
Biosensors, ultra-microscopy, ultra-thin films, bio-functionalization, cell culture
1993-1994 Co-founder and part-time manager of the scientific services company MiNT, München
1992-1993 Graduation in Physics, Diploma. Technische Universität München.
Thesis: " Polymerizable diacetylene lipids on the air/water interface"
1987-1992 Undergraduate studies in Technical Physics, Technische Universität München. Specializing in medical electronics and medical radiological physics.
1985-1987 Officer track in the German Army medical service
1985 High School Graduation
2002
P.
Norlin,
M.
Kindlundh,
A.
Mouroux,
K.
Yoshida,
W.
Jensen, and
U. G.
Hofmann,
A 32-site neural recording probe fabricated by DRIE of SOI substrates, J. Micromechanics Microeng. , vol. 12, pp. 414-419, 2002.
A 32-site neural recording probe fabricated by DRIE of SOI substrates, J. Micromechanics Microeng. , vol. 12, pp. 414-419, 2002.
| File: |  Norlin_et_al__JMM_2002.pdf
|
| Bibtex: |  @ARTICLE{NorlinJMM2002,
author = {P. Norlin and M. Kindlundh and A. Mouroux and K. Yoshida and W. Jensen
and U. G. Hofmann},
title = {A 32-site neural recording probe fabricated by DRIE of SOI substrates},
journal = {J. Micromechanics Microeng.},
year = {2002},
volume = {12},
pages = {414-419}
}
|
U. G.
Hofmann,
A.
Folkers,
F.
Mösch,
F.
Höhl,
M.
Kindlundh, and
P.
Norlin,
A 64(128)-channel multisite neuronal recording system, Biomedizinische Technik , vol. 47(E 1), pp. 194-197, 2002.
A 64(128)-channel multisite neuronal recording system, Biomedizinische Technik , vol. 47(E 1), pp. 194-197, 2002.
| File: | Hofmann_BMT_01.pdf
|
| Bibtex: | @ARTICLE{HofmannBMT2002,
author = {U. G. Hofmann and A. Folkers and F. Mösch and F. Höhl and M. Kindlundh and P. Norlin},
title = {A 64(128)-channel multisite neuronal recording system},
journal = {Biomedizinische Technik},
year = {2002},
volume = {47(E 1)},
pages = {194-197}
}
|
M.
Lipphard,
F.
Eberhardt, and
U. G.
Hofmann,
A Matlab program to quantify low-SNR pacemaker signals, in IFMBE - 12th Nordic Baltic Conference on Biomedical Engineering and Medical Physics. , Reykjavik , 2002.
A Matlab program to quantify low-SNR pacemaker signals, in IFMBE - 12th Nordic Baltic Conference on Biomedical Engineering and Medical Physics. , Reykjavik , 2002.
| File: | Lipphard_NBC02_netz.pdf
|
| Bibtex: | @INPROCEEDINGS{LipphardNBC02,
author = {M. Lipphard and F. Eberhardt and U. G. Hofmann},
title = {A Matlab program to quantify low-SNR pacemaker signals},
booktitle = {IFMBE - 12th Nordic Baltic Conference on Biomedical Engineering and
Medical Physics.},
year = {2002},
address = {Reykjavik},
organization = {International Federation for Medical \& Biological Engineering}
}
|
P.
Fagerstedt,
A.
Volny-Luraghi,
M.
Kindlundh,
P.
Norlin,
U.
Hofmann, and
E.
DeSchutter,
A new type of silicon probes with multi-site microelectrodes for single unit and local field potential (LFP) recordings from cerebellar cortex of anesthetized rats, in Forum of European Neurosciences - Abstracts. 2002 , Paris , 2002.
A new type of silicon probes with multi-site microelectrodes for single unit and local field potential (LFP) recordings from cerebellar cortex of anesthetized rats, in Forum of European Neurosciences - Abstracts. 2002 , Paris , 2002.
| File: | FENS_Patrik.pdf
|
| Bibtex: | @INPROCEEDINGS{FagerstedtFENS2002,
author = {P. Fagerstedt and A. Volny-Luraghi and M. Kindlundh and P. Norlin
and U. Hofmann and E. DeSchutter},
title = {A new type of silicon probes with multi-site microelectrodes for
single unit and local field potential (LFP) recordings from cerebellar
cortex of anesthetized rats},
booktitle = {Forum of European Neurosciences - Abstracts. 2002},
year = {2002},
address = {Paris}
}
|
K. M. L.
Menne,
R.
Maex R, and
U. G.
Hofmann,
A realistical simulation of a small CA3 network to benchmark spike sorting algorithms and feature detection, in Poster and Abstract, Forum of European Neurosciences , Paris , 2002.
A realistical simulation of a small CA3 network to benchmark spike sorting algorithms and feature detection, in Poster and Abstract, Forum of European Neurosciences , Paris , 2002.
| Bibtex: | @INPROCEEDINGS{MenneFens2002,
author = {Menne, K. M. L. and Maex R, R. and Hofmann, U. G.},
title = {A realistical simulation of a small CA3 network to benchmark spike
sorting algorithms and feature detection},
booktitle = {Poster and Abstract, Forum of European Neurosciences},
year = {2002},
volume = {Abstr. vol.1, A090.12},
address = {Paris}
}
|
G.
Biella,
L.
Uva,
U. G.
Hofmann, and
M.
deCurtis,
Associative interactions within the superficial layers of the entorhinal cortex of the guinea pig, J. Neurophysiology , vol. 88, no. 3, pp. 1159-1165, 2002.
Associative interactions within the superficial layers of the entorhinal cortex of the guinea pig, J. Neurophysiology , vol. 88, no. 3, pp. 1159-1165, 2002.
| File: | Biella_JN2002_88_1159_01.pdf
|
| Bibtex: | @ARTICLE{Biella_JN88_2002,
author = {G. Biella and L. Uva and U. G. Hofmann and M. deCurtis},
title = {Associative interactions within the superficial layers of the entorhinal
cortex of the guinea pig},
journal = {J. Neurophysiology},
year = {2002},
volume = {88},
pages = {1159-1165},
number = {3}
}
|
K. M. L.
Menne,
R.
Maex, and
U. G.
Hofmann,
Biologically realistic simulated extracellular potential data as benchmark for the evaluation of spike detection algorithms, in Poster and Abstract, CNS2002 , Chicago , 2002.
Biologically realistic simulated extracellular potential data as benchmark for the evaluation of spike detection algorithms, in Poster and Abstract, CNS2002 , Chicago , 2002.
| Bibtex: | @INPROCEEDINGS{MenneCNS2002,
author = {K. M. L. Menne and R. Maex and U. G. Hofmann},
title = {Biologically realistic simulated extracellular potential data as
benchmark for the evaluation of spike detection algorithms},
booktitle = {Poster and Abstract, CNS2002},
year = {2002},
address = {Chicago}
}
|
K. M. L.
Menne,
T.
Malina, and
U. G.
Hofmann,
Biologically realistic simulation of a part of hippocampal CA3: Generation of testdata for the evaluation of spike detection algorithms, in 5th German Workshop on Artificial Life - Abstracting and Synthesizing the Principles of Living Systems , D. Polani and J. Kim and T. Martinetz, Eds. Lübeck: IOS Press Infix, 2002. pp. 17-25.
Biologically realistic simulation of a part of hippocampal CA3: Generation of testdata for the evaluation of spike detection algorithms, in 5th German Workshop on Artificial Life - Abstracting and Synthesizing the Principles of Living Systems , D. Polani and J. Kim and T. Martinetz, Eds. Lübeck: IOS Press Infix, 2002. pp. 17-25.
| File: | Menne_GWAL5_01.pdf
|
| Bibtex: | @INPROCEEDINGS{MenneGWAL5-2002,
author = {K. M. L. Menne and T. Malina and U. G. Hofmann},
title = {Biologically realistic simulation of a part of hippocampal CA3: Generation
of testdata for the evaluation of spike detection algorithms},
booktitle = {5th German Workshop on Artificial Life - Abstracting and Synthesizing
the Principles of Living Systems},
year = {2002},
editor = {D. Polani and J. Kim and T. Martinetz},
pages = {17-25},
address = {Lübeck},
publisher = {IOS Press Infix}
}
|
M.
Kindlundh,
P.
Norlin, and
U. G.
Hofmann,
Development of multisite microelectrodes for neuroscience, in Proceedings of the Micro Structure Workshop MSW'02 , Aronsborg, Sweden , 2002. pp. B8.1-B8.6.
Development of multisite microelectrodes for neuroscience, in Proceedings of the Micro Structure Workshop MSW'02 , Aronsborg, Sweden , 2002. pp. B8.1-B8.6.
| File: | Kindlundh_MSW-02_01.pdf
|
| Bibtex: | @INPROCEEDINGS{KindlundhMWS2002,
author = {M. Kindlundh and P. Norlin and U. G. Hofmann},
title = {Development of multisite microelectrodes for neuroscience},
booktitle = {Proceedings of the Micro Structure Workshop MSW'02},
year = {2002},
pages = {B8.1-B8.6},
address = {Aronsborg, Sweden}
}
|
H.
Schuhart,
K. M. L.
Menne, and
U. G.
Hofmann,
GROGRA and GENESIS: in computo grown neurons used for realistic compartmental modeling, in Poster and Abstract, CNS2002 , Chicago , 2002.
GROGRA and GENESIS: in computo grown neurons used for realistic compartmental modeling, in Poster and Abstract, CNS2002 , Chicago , 2002.
| Bibtex: | @INPROCEEDINGS{SchuhartCNR2002,
author = {H. Schuhart and K. M. L. Menne and U. G. Hofmann},
title = {GROGRA and GENESIS: in computo grown neurons used for realistic compartmental
modeling},
booktitle = {Poster and Abstract, CNS2002},
year = {2002},
address = {Chicago}
}
|
G. R.
Biella,
L.
Uva,
U. G.
Hofmann, and
M.
deCurtis,
Intrinsic and associative synaptic circuit in the temporal neocortex, perirhinal and enotrhinal cortex: an intra- and extracellular electrophysiological study, in Forum of European Neurosciences - Abstracts , Paris , 2002.
Intrinsic and associative synaptic circuit in the temporal neocortex, perirhinal and enotrhinal cortex: an intra- and extracellular electrophysiological study, in Forum of European Neurosciences - Abstracts , Paris , 2002.
| File: | FENS_Gerardo_01.pdf
|
| Bibtex: | @INPROCEEDINGS{BiellaFENS2002,
author = {G. R. Biella and L. Uva and U. G. Hofmann and M. deCurtis},
title = {Intrinsic and associative synaptic circuit in the temporal neocortex,
perirhinal and enotrhinal cortex: an intra- and extracellular electrophysiological
study},
booktitle = {Forum of European Neurosciences - Abstracts},
year = {2002},
address = {Paris}
}
|
U. G.
Hofmann,
U.
Knopp,
J.
Modersitzki, and
B.
Fischer,
Navigationshilfsvorrichtung für neurochirurgische Eingriffe am menschlichen Gehirn, 2002. Eingereicht zum Deutschen Patent, DE 10242802.6.
Navigationshilfsvorrichtung für neurochirurgische Eingriffe am menschlichen Gehirn, 2002. Eingereicht zum Deutschen Patent, DE 10242802.6.
| Bibtex: | @MISC{HofmannPatent2002,
author = {U. G. Hofmann and U. Knopp and J. Modersitzki and B. Fischer},
title = {Navigationshilfsvorrichtung für neurochirurgische Eingriffe am menschlichen
Gehirn},
howpublished = {Eingereicht zum Deutschen Patent, DE 10242802.6},
year = {2002}
}
|
P.
Norlin,
M.
Kindlundh, and
U.
Hofmann,
Probe suitable for use in neural tissue., .... Swedish Patent Pending 2002, European Patent Pending EP 1389442 A1, 2002.
Probe suitable for use in neural tissue., .... Swedish Patent Pending 2002, European Patent Pending EP 1389442 A1, 2002.
| Bibtex: | @Book{HofmannSwedishPatent2002,
title = {Probe suitable for use in neural tissue},
publisher = {Swedish Patent Pending 2002, European Patent Pending EP 1389442 A1},
year = {2002},
author = {Norlin, P. and Kindlundh, M. and Hofmann, U.},
} |
T.
Malina,
A.
Folkers, and
U. G.
Hofmann,
Real-time EEG processing based on Wavelet Transformation, in IFMBE - 12th Nordic Baltic Conference on Biomedical Engineering and Medical Physics , Reykjavik , 2002.
Real-time EEG processing based on Wavelet Transformation, in IFMBE - 12th Nordic Baltic Conference on Biomedical Engineering and Medical Physics , Reykjavik , 2002.
| File: | Malina_NBC02-netz_01.pdf
|
| Bibtex: | @INPROCEEDINGS{MalinaNBC2002,
author = {T. Malina and A. Folkers and U. G. Hofmann},
title = {Real-time EEG processing based on Wavelet Transformation},
booktitle = {IFMBE - 12th Nordic Baltic Conference on Biomedical Engineering and
Medical Physics},
year = {2002},
address = {Reykjavik},
organization = {International Federation for Medical \& Biological Engineering}
}
|
U. G.
Hofmann,
W.
Jensen,
K.
Yoshida,
M.
Kindlundh, and
P.
Norlin,
Silizium-Vielfachsonden für die Neurowissenschaften, FOCUS MUL , vol. 19, no. 3, pp. 132-139, 2002.
Silizium-Vielfachsonden für die Neurowissenschaften, FOCUS MUL , vol. 19, no. 3, pp. 132-139, 2002.
| File: | Hofmann_FOCUS_MUL02_full_01.pdf
|
| Bibtex: | @ARTICLE{HofmannFocusMUL2002,
author = {U. G. Hofmann and W. Jensen and K. Yoshida and M. Kindlundh and P. Norlin},
title = {Silizium-Vielfachsonden für die Neurowissenschaften},
journal = {FOCUS MUL},
year = {2002},
volume = {19},
pages = {132-139},
number = {3}
}
|
W.
Freiwald,
A.
Wannig,
A. K.
Kreiter,
U. G.
Hofmann,
M. D.
Hills,
G.T.A.
Kovacs,
D. T.
Kewley,
J. M.
Bower,
C. E.
Eurich, and
S. D.
Wilke,
Stimulus representation in rat primary visual cortex: multi-electrode recordings with micromachined silicon probes and estimation theory, Neurocomputing , vol. 44-46, pp. 407-416, 2002.
Stimulus representation in rat primary visual cortex: multi-electrode recordings with micromachined silicon probes and estimation theory, Neurocomputing , vol. 44-46, pp. 407-416, 2002.
| File: | Freiwald_NEUCOM_02.pdf
|
| Bibtex: | @ARTICLE{FreiwaldNEUCOM2002,
author = {W. Freiwald and A. Wannig and A. K. Kreiter and U. G. Hofmann and M. D. Hills and G.T.A. Kovacs and D. T. Kewley and J. M. Bower and C. E. Eurich and S. D. Wilke},
title = {Stimulus representation in rat primary visual cortex: multi-electrode recordings with micromachined silicon probes and estimation theory},
journal = {Neurocomputing},
year = {2002},
volume = {44-46},
pages = {407-416}
}
|
K. M. L.
Menne,
A.
Folkers,
T.
Malina,
R.
Maex, and
U. G.
Hofmann,
Test of spike sorting algorithms on the basis of simulated network data, Neurocomputing 44-46 , vol. 44-46, pp. 1119-1126, 2002.
Test of spike sorting algorithms on the basis of simulated network data, Neurocomputing 44-46 , vol. 44-46, pp. 1119-1126, 2002.
| File: | Menne_NEUCOM_01.pdf
|
| Bibtex: | @ARTICLE{MenneNEUCOM2002,
author = {K. M. L. Menne and A. Folkers and T. Malina and R. Maex and U. G.
Hofmann},
title = {Test of spike sorting algorithms on the basis of simulated network
data},
journal = {Neurocomputing 44-46},
year = {2002},
volume = {44-46},
pages = {1119-1126}
}
|
2001
P.
Norlin,
M.
Kindlundh,
A.
Mouroux,
K.
Yoshida,
W.
Jensen, and
U. G.
Hofmann,
A 32-site neural recording probe fabricated by double-sided deep reactive ion etching of Silicon-on-Insulator substrates, in Micromechanics Europe Workshop (MME-2001) , Cork, Ireland , 2001.
A 32-site neural recording probe fabricated by double-sided deep reactive ion etching of Silicon-on-Insulator substrates, in Micromechanics Europe Workshop (MME-2001) , Cork, Ireland , 2001.
| File: | Norlin_et_al__MMW.pdf
|
| Bibtex: | @INPROCEEDINGS{NorlinMME01,
author = {P. Norlin and M. Kindlundh and A. Mouroux and K. Yoshida and W. Jensen
and U. G. Hofmann},
title = {A 32-site neural recording probe fabricated by double-sided deep
reactive ion etching of Silicon-on-Insulator substrates},
booktitle = {Micromechanics Europe Workshop (MME-2001)},
year = {2001},
address = {Cork, Ireland}
}
|
A.
Folkers, and
U. G.
Hofmann,
A multichannel data acquisition and analysis system based on off-the-shelf DSP boards, in Proceedings of the EURASIP Conference on Digital Signal Processing for Multimedia Communications and Services (ECMCS) , K. Fazekas, Eds. Scientific Association of Infocommunications - HTE, 2001. pp. 249-252.
A multichannel data acquisition and analysis system based on off-the-shelf DSP boards, in Proceedings of the EURASIP Conference on Digital Signal Processing for Multimedia Communications and Services (ECMCS) , K. Fazekas, Eds. Scientific Association of Infocommunications - HTE, 2001. pp. 249-252.
| File: | Folkers_Hofmann_ECMCS_01.pdf
|
| Bibtex: | @INPROCEEDINGS{FolkersHofmannECMCS01,
author = {A. Folkers and U. G. Hofmann},
title = {A multichannel data acquisition and analysis system based on off-the-shelf
DSP boards},
booktitle = {Proceedings of the EURASIP Conference on Digital Signal Processing
for Multimedia Communications and Services (ECMCS)},
year = {2001},
editor = {K. Fazekas},
pages = {249-252},
publisher = {Scientific Association of Infocommunications - HTE}
}
|
T.
Malina,
A.
Folkers,
F.
Mösch,
K.
Labusch,
M.
Schürmann, and
U. G.
Hofmann,
An integrated system to trigger feedback-coupled event related brain potentials (ERPs), Biomedizinsche Technik , vol. 46, no. E1, pp. 322-323, 2001.
An integrated system to trigger feedback-coupled event related brain potentials (ERPs), Biomedizinsche Technik , vol. 46, no. E1, pp. 322-323, 2001.
| File: | Malina_BMT01.netz_01.pdf
|
| Bibtex: | @ARTICLE{MalinaBMT2001,
author = {T. Malina and A. Folkers and F. Mösch and K. Labusch and M. Schürmann
and U. G. Hofmann},
journal = {In: J. Werner (Ed.), 46 E1, , Schiele \& Sch{\"o}n GmbH, Bochum},
title = {An integrated system to trigger feedback-coupled event related brain
potentials (ERPs)},
journal = {Biomedizinsche Technik},
year = {2001},
volume = {46},
pages = {322-323},
number = {E1}
}
|
K.
Yoshida,
W.
Jensen,
P.
Norlin,
M.
Kindlundh, and
U. G.
Hofmann,
Characterization of silicon microelectrodes from the EU VSAMUEL project, Biomedizinsche Technik , vol. 46, no. E1, pp. 446-447, 2001.
Characterization of silicon microelectrodes from the EU VSAMUEL project, Biomedizinsche Technik , vol. 46, no. E1, pp. 446-447, 2001.
| File: | Yoshida_BMT01.pdf
|
| Bibtex: | @ARTICLE{YoshidaBMT01,
author = {K. Yoshida and W. Jensen and P. Norlin and M. Kindlundh and U. G.
Hofmann},
title = {Characterization of silicon microelectrodes from the EU VSAMUEL project},
journal = {Biomedizinsche Technik},
year = {2001},
volume = {46},
pages = {446-447},
number = {E1}
}
|
U. G.
Hofmann, and
J.
Peltonen,
Colour transitions in monolayers of a polymerizable single chain diacetylenic lipid, Langmuir , vol. 17, pp. 1518-24, 2001.
Colour transitions in monolayers of a polymerizable single chain diacetylenic lipid, Langmuir , vol. 17, pp. 1518-24, 2001.
| File: | la17-2001-Jouko.pdf
|
| Bibtex: | @ARTICLE{La17Jouko2001,
author = {U. G. Hofmann and J. Peltonen},
title = {Colour transitions in monolayers of a polymerizable single chain
diacetylenic lipid},
journal = {Langmuir},
year = {2001},
volume = {17},
pages = {1518-24}
}
|
U. G.
Hofmann,
J.
Thompson, and
D. T.
Kewley,
Electrophysiological depth profiling by multiunit microelectrodes for stereotactic neurosurgery, 2001. US Patent No. 6,330,466, California Institute of Technology, USA.
Electrophysiological depth profiling by multiunit microelectrodes for stereotactic neurosurgery, 2001. US Patent No. 6,330,466, California Institute of Technology, USA.
| Bibtex: | @MISC{HOF01a,
author = {U. G. Hofmann and J. Thompson and D. T. Kewley},
title = {Electrophysiological depth profiling by multiunit microelectrodes
for stereotactic neurosurgery},
howpublished = {US Patent No. 6,330,466, California Institute of Technology, USA},
year = {2001}
}
|
K. M. L.
Menne,
R.
Maex, and
U. G.
Hofmann,
Extracellular potential data generated in a network simulation, in Poster and Abstract, The Neurosciences at the Turn of the Century, Proceedings of the 4th Meeting of the German Neuroscience Society , Göttingen: Georg Thieme Verlag, 2001.
Extracellular potential data generated in a network simulation, in Poster and Abstract, The Neurosciences at the Turn of the Century, Proceedings of the 4th Meeting of the German Neuroscience Society , Göttingen: Georg Thieme Verlag, 2001.
| Bibtex: | @INPROCEEDINGS{MEN01a,
author = {K. M. L. Menne and R. Maex and U. G. Hofmann},
title = {Extracellular potential data generated in a network simulation},
booktitle = {Poster and Abstract, The Neurosciences at the Turn of the Century,
Proceedings of the 4th Meeting of the German Neuroscience Society},
year = {2001},
volume = {1},
number = {602},
address = {Göttingen},
publisher = {Georg Thieme Verlag}
}
|
B.
Weber,
T.
Malina,
K.
Menne,
V.
Metzler,
A.
Folkers, and
U. G.
Hofmann,
Handling large files of multisite microelectrode recordings for the European VSAMUEL consortium, Neurocomputing , vol. 38-40, pp. 1725-1734, 2001.
Handling large files of multisite microelectrode recordings for the European VSAMUEL consortium, Neurocomputing , vol. 38-40, pp. 1725-1734, 2001.
| File: | Weber-NEUCOM_01p.pdf
|
| Bibtex: | @ARTICLE{WeberNEUCOM01,
author = {B. Weber and T. Malina and K. Menne and V. Metzler and A. Folkers
and U. G. Hofmann},
title = {Handling large files of multisite microelectrode recordings for the
European VSAMUEL consortium},
journal = {Neurocomputing},
year = {2001},
volume = {38-40},
pages = {1725-1734}
}
|
