Vessel Segmentation and Analysis

This project is the result of a long established collaboration between ISIP and medical research partners.

2D projection imaging - like e.g. angiograms and photographies - is a widely used procedure for vessel visualization. 

The segmentation of blood vessels in such images is important not only in the clinical routine, for diagnosis and treatment purposes but also in biometrics (retina vessels) and during evaluation of scientific experiments -e.g. as those aimed at improving the vascularization of transplated skin.

Project Goal

Within the frame of this project we aim at developing specific vessel segmentation algorithms as well as novel vessel enhancement and vessel analysis techniques.

Project Partners

Klinik für Plastische und Handchirurgie, Unversitätsklinikum Schleswig-Holstein/Campus Lübeck

Software

The VesSeg software tool makes use of some of the algorithms developed within the frame of this project to allow researchers to semi-automatically segment vascular networks in tissue-engineering skin.

Download: The latest version of the VesSeg software tool can be downloaded here.

Publications

2012

  • Condurache, A. P. and Mertins, A.: Segmentation of retinal vessels with a hysteresis binary-classification paradigm. Computerized Medical Imaging and Graphics, vol. 36, no. 4, pp. 325-335, 2012
    BibTeX PDF

2010

  • Condurache, A. P., Müller, F., and Mertins, A.: An LDA-based relative hysteresis classifier with application to segmentation of retinal vessels. Proc. Int. Conf. Pattern Recognition (ICPR), Istanbul, Turkey, pp. 4202--4205, Sept. 2010
    BibTeX PDF

2009

  • Condurache, A. P., Mertins, A., and Aach, T.: Supervised, hysteresis-based segmentation of retinal images using the linear-classifier percentile. Medizinische Bildverarbeitung und Mustererkennung (GI Jahrestagung), Lübeck, Lecture Notes in Informatics, vol. P154, pp. 1285--1293, Oct. 2009
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2008

  • Egana, J., Condurache, A. P., Lohmeyer, J., Kremer, M., Stoeckelhuber, B. M., Lavandero, S., and Machens, H.: Ex vivo method to visualize and quantify vascular networks in native and tissue engineering skin. Langenbeck's Archives of Surgery
    BibTeX

2006

  • Machens, H. G., Grzybowski, S., Bucsky, B., Niedworok, a. . T. S. C., Maichle, A., Stockelhuber, B., Condurache, A., Liu, F., Egana, J. T., Kaun, M., Mailander, P., and Aach, T.: Technique to Detect and to Quantify Fasciocutaneous Blood Vessels in Small Laboratory Animals Ex Vivo. Journal of Surgical Research, vol. 131, no. 1, pp. 91-96, March 2006
    BibTeX
  • Condurache, A. P. and Aach, T.: Vessel segmentation in 2D-projection images using a supervised linear hysteresis classifier.. Proceedings of ICPR-2006, IEEE, Hong Kong, China, vol. 1, pp. 239-243, August 20-24 2006
    BibTeX PDF

2005

  • Condurache, A. P. and Aach, T.: Vessel segmentation in angiograms using hysteresis thresholding.,. Proceedings of MVA-2005,, Tsukuba, Japan,, pp. 269-272,, May 16-18, 2005
    BibTeX PDF
  • Condurache, A. P., Aach, T., Grzybowski, S., and Machens, H.: Vessel segmentation and analysis in laboratory skin transplant micro-angiogram.. Proceedings of the 18 th IEEE Symposium on CBMS-2005, IEEE, Dublin, Ireland, pp. 21-26, June 23-24 2005
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  • Condurache, A. P., Aach, T., Grzybowski, S., and Machens, H.: Imaging and analysis of angiogenesis for skin transplantation by microangiography.. Proceedings of ICIP-2005, IEEE, Genoa, Italy, pp. II/1250 - II/1253 (also on CD-ROM: ISBN 07803 9135-7), September 11-14 2005
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2004

  • Grzybowski, S., Bucsky, B., Stoeckelhuber, B., Aach, T., Condurache, A., Mailaender, P., and Machens, H. G.: A Microangiography Technique to Quantify Fasciocutaneous Blood Vessels in Small Laboratory Animals. , vol. 389, no. 10, , 2004
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  • Grzybowski, S., Bucsky, B., Stoeckelhuber, B., Aach, T., Condurache, A., Lindenmaier, W., and Mailaender, P.: Model for Induction of Angiogenesis by Synergetic Effects of BFGF by Bioactive Dermal Matrices. , vol. 389, no. 10, , 2004
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